Preview
Written by Yaro Pavlenko
Spreadex Sports previews the upcoming 2025/26 FA Cup quarter-final fixture between Southampton and Arsenal. The Gunners' hopes of a quadruple may have ended after defeat in the Carabao Cup final, but they will be looking to go one better in a competition they've won more than anyone else. The next step towards that will be taking on Championship opposition here.
Southampton, meanwhile, are honouring the 50-year anniversary of their one and only FA Cup victory with an impressive run this season, and knocked out Premier League opposition Fulham last time out. Can they produce a massive shock here to reach the semi-finals and a trip to Wembley?
When is Southampton v Arsenal? Saturday, April 4th 2026.
What time is kick-off for Southampton v Arsenal?8pm, UK time.
Where is Southampton v Arsenal being played? St. Mary's Stadium, Southampton.
How can I watch Southampton v Arsenal? Live on BBC One from 8pm.
Although the Saints will be the underdogs here, they are on an excellent run of form leading into this one. They have lost just twice in 2026, and are on a run of 14 matches unbeaten with three wins in their last three fixtures.
Arsenal, meanwhile, are still alive in the Champions League and are perched at the top of the Premier League, so a historic treble is still very much on the table. Can they make their return after the international break and put the disappointment of the Carabao Cup defeat last time out behind them?
WIN: Southampton 2-0 Oxford Utd. 21st March 2026.WIN: Southampton 1-0 Norwich. 18th March 2026. WIN: Coventry 1-2 Southampton. 14th March 2026.
LOSS: Arsenal 0-2 Man City. 22nd March 2026.WIN: Arsenal 2-0 Bayer Leverkusen. 17th March 2026.WIN: Arsenal 2-0 Everton. 14th March 2026.
To see all the Southampton v Arsenal betting stats and form, visit our pricing page to view our Pre-Match betting stats table or hover over/tap the chart image to see previous outcomes for that particular market.
The Spreadex Sports fixed odds Match Odds betting prices have Arsenal as heavy 1/4 favourites to secure a victory while our 2 Up early pay out market, which pays out when a team goes two goals up, has the Gunners also at 1/4.
Southampton meanwhile are available at 9/1 for the home victory (8/1 on our 2 Up market), with the draw at 5/1.
H2H form has seen the last five meetings produce two draws, two wins for Arsenal and one for Southampton. The last St Mary's meeting saw Arsenal come away with a tight 2-1 victory.
Six of the last ten meetings saw Both Teams Scoring, you can back Both to Score - Yes at Evens here.
To Qualify odds have Southampton at 11/2 and Arsenal at 1/10.
Our football spread betting prices have the Goal Supremacy as Arsenal/Southampton (h) 1.7 - 1.9. This means if Arsenal won 4-1 (or by any other three goal margin), a 'buy' bet at 1.9 would mean a return of 1.1x your initial stake.
However, if you bought at 1.9 in Arsenal's favour and the match ended goalless, you would lose 1.9x your stake. Or, if Southampton were to grab a 1-0 (or any other one goal margin) win, the market would settle negatively at -1 and a buy at 1.9 would result in a loss of 2.9x your opening stake.
You can calculate various make-ups by using our handy spread betting calculator, found here.
Our spread betting Total Goals line is 3.2 - 3.4. So a 3.4 'buy' bet would need at least four goals to be scored in the match to start turning a profit. Conversely, a 3.2 sell bet would need less than three goals to be scored in the match to turn a profit.
Remember that with spread betting, get the bet wrong and losses can exceed your stake/deposit. E.g. a 3.4 'buy' Total Goals bet would lose 3.4x your opening stake if the match ended 0-0, and so on.
We have several pre-built Popular Bet-Builders, including Arsenal to win, Over 6.5 Arsenal corners, Over 2.5 Southampton cards & Over 3.5 goals - 7/1, Arsenal to win, Arsenal most corners & Southampton most cards - 13/8 and much more!
Price Boosts for this one will be available sooner to kick-off time.
Spreadex offers football spread betting prices on Southampton v Arsenal, as well as traditional sportsbook/fixed odds prices.
Some of these markets include options such as Player Goal Minutes (the aggregate minutes of the goals scored by a named player in a match), Total Goal Minutes (the aggregate of the minutes of all goals scored in a match), Shirt Numbers (the aggregate of the shirt numbers of all goalscorers in a match), Bookings Points (based on 10 points per yellow, 25 per red), Corners, Time of 1st Match Goal, Match Performance and many, many more.
See our football spread betting education centre to see examples of how spread betting works, watch short explainer videos and try interactive betting widgets to see how win or loss levels work on different bets.
Remember that with spread betting, get the bet wrong and losses can exceed your stake/deposit so it's important you understand how each market works before setting an appropriate stake size for your bet.
Visit our football spread betting education area here.
Please note that this preview is not designed to offer any betting advice or suggestions. All prices quoted correct as of 11am Thursday 2nd April. Price Boosts and other markets will be added closer to kick-off time.
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